Britain's women finished fifth in the 4x400m relay final at the Olympic Stadium.
The United States quartet of DeeDee Trotter, Allyson Felix, Francena McCorory and Sanya Richards-Ross cruised to victory ahead of Russia and Jamaica.
Individual silver medallist Christine Ohuruogu was on the final leg, with Shana Cox, Lee McConnell and Perri Shakes-Drayton contesting the other legs.
Ohuruogu said: "I knew it was going to be hard, I was trying to run and catch the Ukrainian, but in front of the Ukrainian was someone else so it was hard."
Shakes-Drayton, who just missed out on a place in the 400m hurdles final, added: "Today we would have loved to have got a medal, but it didn't go our way. But as a whole, as a team, we've done very well. We've run a season's best (3:24.76), that's the best we've ever run together.
"I had unfinished business to do considering what happened in my own event so I went out there and gave it all I could do."