Team GB will look to improve on their record-breaking medal tally - which now stands at 50, making this the most successful overseas Games ever for Great Britain.
Hannah Mills and Saskia Clark just have to finish their women’s 470 sailing race to upgrade the silver they won in London.
And Great Britain’s hockey women are in semi-final action.
Athletics, women’s 200m final (02:30 UK Time)
Dina Asher-Smith, the fastest women in British history over the 100m and 200m, will contest the women’s 200m final at what are her first Olympic Games.
A kit carrier at London 2012, the 20-year-old has become GB’s leading female sprinter over the last few years, setting her personal best of 22.07 seconds at the World Championships last year.
It will be a tall order for Asher-Smith to get among the medals, despite her status at European champion over the distance.
But having come through the toughest of the three semi-finals – she finished fourth behind world champion Dafne Schippers of the Netherlands, Jamaica’s Elaine Thompson and USA’s Deajah Stevens – she will have no pressure on her in Wednesday’s final.
Hockey, women’s semi-final (21:00 UK Time)
Unbeaten in Rio, Great Britain’s women’s hockey team haven’t put a foot wrong in reaching the semi-finals with six straight victories.
A 3-1 win over Spain in the quarter-finals booked a last-four clash with New Zealand – a repeat of the semi-final in London four years ago, which the Black Sticks triumphed in.
Captain Kate Richardson-Walsh will be looking to lead her side to an Olympic finals where either Germany or defending Olympic champions the Netherlands await.
In their most recent encounter, New Zealand were narrow 1-0 winners.
Athletics, 5,000m heats (14:05 UK Time)
Mo Farah has already created his own bit of history in Rio, becoming the first British track and field athlete to win three Olympic gold medals when he won the 10,000m last Saturday.
But he could rewrite another page in the record books when he starts his bid to win 5,000m gold, the other title he won in London.
The 33-year-old would become the first man since Finland’s Lasse Viren in 1976 to retain two Olympic distance titles should he triumph in Brazil.
Farah goes in heat one on Wednesday.
Golf, first round (tees-off 11.20am)
Catriona Matthew recorded an impressive fifth place finish at the recent British Open, so arrives in Rio brimming with confidence.
Her first Olympic memory is watching Alan Wells win 100m gold in Moscow and she admits to being inspired by Justin Rose’s win in the golf. Charley Hull is the other British golfer competing.
Diving, 10m platform qualifying (7pm)
It’s been a difficult build-up for Sarah Barrow, who won European gold two years ago.
After overcoming her shin injuries she makes her second Olympic appearance in Rio, having finish fifth in the 10m synchro event with Tonia Couch at London 2012. Couch, the silver medallist at the most recent Europeans, also competes again.
Sportsbeat 2016